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APOBEC3A Protein, Human, Recombinant (His & SUMO)

APOBEC3A Protein, Human, Recombinant (His & SUMO)

产品编号 TMPH-01235
别名: A3A, APOBEC3A, DNA dC->dU-editing enzyme APOBEC-3A, Phorbolin-1

DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

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APOBEC3A Protein, Human, Recombinant (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 20日内发货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: APOBEC3A Protein, Human, Recombinant (His & SUMO) (TMPH-01235)
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生物活性
技术参数
产品性质
产品描述 DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
种属 Human
表达系统 E. coli
标签 N-terminal 6xHis-SUMO-tagged
蛋白编号 P31941
别名 A3A, APOBEC3A, DNA dC->dU-editing enzyme APOBEC-3A, Phorbolin-1
氨基酸序列 MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
蛋白构建 1-199 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 39.0 kDa (predicted)
缓冲液 Tris-based buffer,50% glycerol
复溶方法 A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

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Keywords

APOBEC3A Protein, Human, Recombinant (His & SUMO) A3A APOBEC3A DNA dC->dU-editing enzyme APOBEC-3A Phorbolin-1 recombinant recombinant-proteins proteins protein

 

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