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Anti-CD16a Antibody (5Q84)

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产品编号 TMAY-03689

Anti-CD16a Antibody (5Q84) 是一种 Rabbit 抗体,靶向 CD16a。Anti-CD16a Antibody (5Q84) 可用于 ELISA。

Anti-CD16a Antibody (5Q84)

Anti-CD16a Antibody (5Q84)

Rating icon 还可以
产品编号 TMAY-03689

Anti-CD16a Antibody (5Q84) 是一种 Rabbit 抗体,靶向 CD16a。Anti-CD16a Antibody (5Q84) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-CD16a Antibody (5Q84) is a Rabbit antibody targeting CD16a. Anti-CD16a Antibody (5Q84) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
5Q84
交叉反应
Rat
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD16a / FCGR3A (TMPY-02018; ABO70343.1; Met1-Pro200).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the Fc portion of various antibodies. CD16a / FCGR3A also has a broader function. CD16a / FCGR3A is directly involved in the lysis of some virus-infected cells and tumor cells by NK cells, independent of antibody binding. Cross-linking of CD16a / FCGR3A on NK cells resulted in increased intracellular Ca2+ levels and a cascade of biochemical events similar to those activated by the T cell receptor. CD16a / FCGR3A on human NK cells is a lysis receptor that mediates the direct killing of some virus infected and tumor cells, independent of antibody ligation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Rat CD16a / FCGR3A protein (TMPY-02018)
抗原种属
Rat
研究领域
Fc Receptors, Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
5.0
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