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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FOXH1 Polyclonal Antibody

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货号 TMAB-06125

Anti-FOXH1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FOXH1。Anti-FOXH1 Polyclonal Antibody 可用于 WB。

Anti-FOXH1 Polyclonal Antibody

Anti-FOXH1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06125

Anti-FOXH1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FOXH1。Anti-FOXH1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOXH1 Polyclonal Antibody is a Rabbit antibody targeting FOXH1. Anti-FOXH1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFG?and activin, indicating that these FAST proteins mediate TFG?induced signal transduction (3).
抗原信息
免疫原
KLH conjugated synthetic peptide: human FOXH1
抗原种属
Human
基因名称
FOXH1
基因ID
8928
蛋白名称
Forkhead box protein H1
Uniprot ID
O75593
功能
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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