规格

价格

库存

数量

2 mg

¥ 1,950

5日内发货

5 mg

¥ 2,890

5日内发货

25 mg

¥ 9,870

6-8周

50 mg

¥ 13,300

6-8周

100 mg

¥ 17,500

6-8周

1 mL x 10 mM (in DMSO)

¥ 4,330

5日内发货

生物活性

产品描述	Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.
体外活性	Rapacuronium accelerates the rate of ACh binding but decreases its affinity under equilibrium conditions.?This results in potentiation of receptor activation at low concentrations of rapacuronium (1 microM) but not at high concentrations (10 microM).?These observations highlight the relevance and necessity of performing physiological tests under non-equilibrium conditions in evaluating the functional effects of allosteric modulators at muscarinic receptors.
体内活性	Time course of the neuromuscular effects of Rapacuronium following the administration of the 2×ED90 doses to rats and guinea-pigs(ED90 of 5953±199 and 187±16 μg/kg in rat and guinea pig, respectively)[2].
别名	Org 9487

化学信息

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 125 mg/mL (184.42 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (4.87 mM), Sonication is recommeded.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO