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Anti-CSF3R/G-CSFR Antibody-APC (4I21)
还可以产品编号 TMAY-00481A
Anti-CSF3R/G-CSFR Antibody-APC (4I21) 是一种 APC-conjugated Mouse 抗体，靶向 CSF3R/G-CSFR。Anti-CSF3R/G-CSFR Antibody-APC (4I21) 可用于 FCM。
Anti-CSF3R/G-CSFR Antibody-APC (4I21)
Anti-CSF3R/G-CSFR Antibody-APC (4I21)
还可以产品编号 TMAY-00481A
Anti-CSF3R/G-CSFR Antibody-APC (4I21) 是一种 APC-conjugated Mouse 抗体，靶向 CSF3R/G-CSFR。Anti-CSF3R/G-CSFR Antibody-APC (4I21) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CSF3R/G-CSFR Antibody-APC (4I21) is a APC-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-APC (4I21) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4I21 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of anti-human GCSFR (CD114) on human whole blood granulocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable granulocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR / CD114 / CSF3R (rh G-CSFR / CD114 / CSF3R; NP_000751.1Met1-Pro621) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human G-CSFR / CD114 / CSF3R Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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