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顶部生物活性储存和溶解信息计算器

Anti-MKLP1 Antibody (7V592)

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Anti-MKLP1 Antibody (7V592)
产品编号 TMAC-02595
别名 MKLP 1, Mitotic kinesin-like protein 1, Mitotic kinesin like protein 1, Mitotic kinesin like 1, KNSL5, KNSL 5, KNS L5, Kinesin-like protein KIF23, Kinesin-like protein 5, Kinesin like protein KIF23, Kinesin like protein KIF 23, Kinesin like protein 5, Kinesin like 5, Kinesin family member 23, KIF23_HUMAN, KIF23, KIF 23, CHO1, CHO 1

Anti-MKLP1 Antibody (7V592) 是一种 Rabbit 抗体，靶向 MKLP1。Anti-MKLP1 Antibody (7V592) 可用于 WB,ICC/IF。

Anti-MKLP1 Antibody (7V592)

Anti-MKLP1 Antibody (7V592)

Rating icon 还可以
Anti-MKLP1 Antibody (7V592)
产品编号 TMAC-02595 别名 MKLP 1, Mitotic kinesin-like protein 1, Mitotic kinesin like protein 1, Mitotic kinesin like 1, KNSL5, KNSL 5, KNS L5, Kinesin-like protein KIF23, Kinesin-like protein 5, Kinesin like protein KIF23, Kinesin like protein KIF 23, Kinesin like protein 5, Kinesin like 5, Kinesin family member 23, KIF23_HUMAN, KIF23, KIF 23, CHO1, CHO 1

Anti-MKLP1 Antibody (7V592) 是一种 Rabbit 抗体，靶向 MKLP1。Anti-MKLP1 Antibody (7V592) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MKLP1 Antibody (7V592) is a Rabbit antibody targeting MKLP1. Anti-MKLP1 Antibody (7V592) can be used in WB,ICC/IF.
别名MKLP 1, Mitotic kinesin-like protein 1, Mitotic kinesin like protein 1, Mitotic kinesin like 1, KNSL5, KNSL 5, KNS L5, Kinesin-like protein KIF23, Kinesin-like protein 5, Kinesin like protein KIF23, Kinesin like protein KIF 23, Kinesin like protein 5, Kinesin like 5, Kinesin family member 23, KIF23_HUMAN, KIF23, KIF 23, CHO1, CHO 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of MKLP1 on different lysates using anti-MKLP1 antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: Hela.
2. ICC staining MKLP1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining MKLP1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000-5000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The monoclonal antibody CHO1 detects a spindle antigen required for mitotic progression. Screening a HeLa cell cDNA expression library with this antibody has been shown to yield a cDNA predicted to encode a protein significantly related within its amino terminal half to the motor ends of members of the kinesin superfamily. Since this similarity does not extend further, it has been suggested that the CHO1 antigen, now designated MKLP-1 (mitotic kinesin-like protein-1), represents a novel kinesin. Sequence analysis has also been shown to predict that MKLP-1 possesses features typical of nuclear proteins. Immunocytological studies have demonstrated that MKLP-1 moves from the nucleus early in mitosis and then to the midbody after cytokinesis. MKLP-1 has been shown to bundle antiparallel microtubules in vitro and to move them at rates comparable to spindle elongation in vivo. A hamster homolog of MKLP-1, designated CHO1 antigen, has also been isolated. Although apparently functionally equivalent with respect to microtubule bundling activity, there are significant differences between the human and hamster proteins at their C-termini, possibly due to alternative splicing or the presence of more than one MKLP-1 locus.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q02241
化学信息
分子量Theoretical: 98 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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