购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10384

Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Bcl-xL (Thr47)。Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2

Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10384

Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Bcl-xL (Thr47)。Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Bcl-xL (Thr47). Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Cow,Horse,Sheep,GuineaPig)
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, centrosome. Note=Mitochondrial membranes and perinuclear envelope. Localizes to the centrosome when phosphorylated at Ser-49.
组织特异性Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景bs-1336P is one synthetic peptide derived from human Bcl-xL. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human BCL2L1 around the phosphorylation site of Thr47
抗原种属
Human
基因名称
BCL2L1
基因ID
598
蛋白名称
Bcl-2-like protein 1
Uniprot ID
Q07817
功能
Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane.
Isoform Bcl-X(S) promotes apoptosis.
化学信息
分子量Theoretical: 26 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 | purchase Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 | Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 cost | order Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 | Anti-Phospho-Bcl-xL (Thr47) Polyclonal Antibody 2 molecular weight