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Anti-Ficolin 1/FCN1 Antibody (7Q606)

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Anti-Ficolin 1/FCN1 Antibody (7Q606)
产品编号 TMAY-01343
别名 ficolin 1, FCNA, FCN1

Anti-Ficolin 1/FCN1 Antibody (7Q606) 是一种 Mouse 抗体,靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (7Q606) 可用于 ELISA(Det)。

Anti-Ficolin 1/FCN1 Antibody (7Q606)

Anti-Ficolin 1/FCN1 Antibody (7Q606)

Rating icon 还可以
Anti-Ficolin 1/FCN1 Antibody (7Q606)
产品编号 TMAY-01343 别名 ficolin 1, FCNA, FCN1

Anti-Ficolin 1/FCN1 Antibody (7Q606) 是一种 Mouse 抗体,靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (7Q606) 可用于 ELISA(Det)。

规格价格库存数量
20 μL
¥ 595
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100 μL
¥ 1,679
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产品介绍

生物活性
产品描述
Anti-Ficolin 1/FCN1 Antibody (7Q606) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (7Q606) can be used in ELISA(Det).
别名ficolin 1, FCNA, FCN1
Ig Type
Mouse IgG1
克隆号
7Q606
交叉反应
Human
应用
ELISA(Det)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FCN1 (rh FCN1; TMPY-01028; NP_001994.2; Met 1-Ala 326). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human FCN1 protein (TMPY-01028)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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