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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Integrin alpha 6 Antibody (1Z257)

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货号 TMAB-07744

Anti-Integrin alpha 6 Antibody (1Z257) 是一种 Rabbit 抗体，靶向 Integrin alpha 6。Anti-Integrin alpha 6 Antibody (1Z257) 可用于 WB。

Anti-Integrin alpha 6 Antibody (1Z257)

Anti-Integrin alpha 6 Antibody (1Z257)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07744

Anti-Integrin alpha 6 Antibody (1Z257) 是一种 Rabbit 抗体，靶向 Integrin alpha 6。Anti-Integrin alpha 6 Antibody (1Z257) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin alpha 6 Antibody (1Z257) is a Rabbit antibody targeting Integrin alpha 6. Anti-Integrin alpha 6 Antibody (1Z257) can be used in WB.
Ig Type
IgG
克隆号
1Z257
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
抗原信息
免疫原
A synthesized peptide: human Integrin alpha 6
抗原种属
Human
基因名称
ITGA6
基因ID
3655
蛋白名称
Integrin alpha-6
Uniprot ID
P23229
功能
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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