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Anti-Integrin alpha 6 Antibody (1Z257)

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货号 TMAB-07744

Anti-Integrin alpha 6 Antibody (1Z257) 是一种 Rabbit 抗体，靶向 Integrin alpha 6。Anti-Integrin alpha 6 Antibody (1Z257) 可用于 WB。

Anti-Integrin alpha 6 Antibody (1Z257)

Anti-Integrin alpha 6 Antibody (1Z257)

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Rating icon 还可以
货号 TMAB-07744

Anti-Integrin alpha 6 Antibody (1Z257) 是一种 Rabbit 抗体，靶向 Integrin alpha 6。Anti-Integrin alpha 6 Antibody (1Z257) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin alpha 6 Antibody (1Z257) is a Rabbit antibody targeting Integrin alpha 6. Anti-Integrin alpha 6 Antibody (1Z257) can be used in WB.
Ig Type
IgG
克隆号
1Z257
反应种属
Human,Mouse,Rat
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with Integrin alpha 6 monoclonal antibody, unconjugated (TMAB-07744) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
抗原信息
免疫原
A synthesized peptide: human Integrin alpha 6
抗原种属
Human
基因名称
ITGA6
基因ID
3655
蛋白名称
Integrin alpha-6
Uniprot ID
P23229
功能
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
化学信息
分子量Theoretical: 127 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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