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Anti-USP14 Antibody (2P900)
还可以产品编号 TMAH-01236
别名 USP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14
Anti-USP14 Antibody (2P900) 是一种抗体，靶向 USP14。Anti-USP14 Antibody (2P900) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。
Anti-USP14 Antibody (2P900)
Anti-USP14 Antibody (2P900)
还可以产品编号 TMAH-01236 别名 USP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14
Anti-USP14 Antibody (2P900) 是一种抗体，靶向 USP14。Anti-USP14 Antibody (2P900) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-USP14 Antibody (2P900) is an antibody targeting USP14. Anti-USP14 Antibody (2P900) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200. |
| 别名 | USP 14, Ubiquitin-specific-processing protease 14, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, TGT, EC 3.4.19.12, Deubiquitinating enzyme 14 |
| Ig Type | Rabbit IgG |
| 克隆号 | 2P900 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: PC3 whole cell lysate, Ntera-2 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate -All lanes: USP14 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 57, 53, 55 kDa -Observed band size: 55-72 kDa 2. Immunofluorescence staining of PC-3 cell with TMAH-01236 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 517-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| 应用 | ELISA, WB, IF |
| 推荐剂量 | WB:1:500-1:2000; IF:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Cell membrane; Peripheral membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human USP14 |
| 抗原种属 | Human |
| 基因ID | 9097 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cell biology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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