Name: Anti-IL-21 Antibody
Brand: TargetMol
SKU: T9901A-1259
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-IL-21 Antibody represents a highly specialized neutralizing monoclonal antibody specifically engineered to target the pro-inflammatory cytokine interleukin-21 (IL-21) with exceptional binding affinity. It effectively facilitates the measurable blockade of the IL-21/IL-21R signaling axis across various preclinical experimental models to evaluate the suppression of Th17/Tfh-mediated immune responses and the reduction of thyroid-specific autoantibodies during strictly monitored laboratory observation periods and functional immune cell assays.
体外活性	在原代甲状腺细胞和患者 PBMC 中，Anti-IL-21 Antibody 中和了 IL-21 并抑制了促炎细胞因子的表达 [1]。
别名	抗IL-21抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	Q9HBE4
靶点	IL-21

储存&溶解度

存储

Anti-IL-21 Antibody