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Anti-FAM126A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FAM126A。Anti-FAM126A Polyclonal Antibody 可用于 WB。
Anti-FAM126A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FAM126A。Anti-FAM126A Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-FAM126A Polyclonal Antibody is a Rabbit antibody targeting FAM126A. Anti-FAM126A Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Dog,Pig,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane. According to PubMed:10910037, it is mainly cytoplasmic while according to PubMed:16951682, it is a membrane protein. |
| 组织特异性 | Widely expressed. Highest levels in heart, brain, placenta, spleen and testis. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Hyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the ∫-catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7. |
| 免疫原 | KLH conjugated synthetic peptide: human FAM126A |
| 抗原种属 | Human |
| 基因名称 | FAM126A |
| 基因ID | |
| 蛋白名称 | Hyccin |
| Uniprot ID | |
| 功能 | May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system. |
| 分子量 | Theoretical: 58 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |