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Anti-CD68 Antibody (4L231)

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货号 TMAB-04054

Anti-CD68 Antibody (4L231) 是一种 Rabbit 抗体,靶向 CD68。Anti-CD68 Antibody (4L231) 可用于 WB,FCM,ICC/IF。

Anti-CD68 Antibody (4L231)

Anti-CD68 Antibody (4L231)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04054

Anti-CD68 Antibody (4L231) 是一种 Rabbit 抗体,靶向 CD68。Anti-CD68 Antibody (4L231) 可用于 WB,FCM,ICC/IF。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD68 Antibody (4L231) is a Rabbit antibody targeting CD68. Anti-CD68 Antibody (4L231) can be used in WB,FCM,ICC/IF.
Ig Type
IgG
克隆号
4L231
反应种属
Human
应用WBFCMICC/IF
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Isoform Short: Cell membrane; Single-pass type I membrane protein. Isoform Long: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.
组织特异性Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD68
抗原种属
Human
基因名称
CD68
基因ID
蛋白名称
Macrosialin
Uniprot ID
功能
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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