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顶部生物活性储存和溶解信息计算器

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody

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Anti-Phospho-MDMX (Ser367) Polyclonal Antibody
产品编号 TMAC-02512
别名 p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody
产品编号 TMAC-02512 别名 p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)

Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MDMX (Ser367)。Anti-Phospho-MDMX (Ser367) Polyclonal Antibody 可用于 WB,IHC-P,IF(paraffin section),ELISA。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MDMX (Ser367) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MDMX (Ser367). Anti-Phospho-MDMX (Ser367) Polyclonal Antibody can be used in WB,IHC-P,IF(paraffin section),ELISA.
别名p-MDMX (Ser367), p-MDMX (S367), MDMX (p-Ser367), MDMX (p-S367)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用
WB
IHC-P
IF(paraffin section)
ELISA
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景MDM4, p53 regulator(MDM4) Homo sapiens This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2011],
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human MDM4 around the phosphorylation site of Ser367. AA range:336-385
抗原种属
human
Uniprot ID
O15151
化学信息
分子量Actual: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pMDMX (Ser367)pMDMX (S367)MDMX (pSer367)MDMX (pS367)MDMX (phospho-Ser367)MDMX (phospho-S367)

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4个月前
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