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Anti-LPIN1 Antibody (6D73)

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货号 TMAB-08374

Anti-LPIN1 Antibody (6D73) 是一种 Rabbit 抗体,靶向 LPIN1。Anti-LPIN1 Antibody (6D73) 可用于 WB,IP。

Anti-LPIN1 Antibody (6D73)

Anti-LPIN1 Antibody (6D73)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08374

Anti-LPIN1 Antibody (6D73) 是一种 Rabbit 抗体,靶向 LPIN1。Anti-LPIN1 Antibody (6D73) 可用于 WB,IP。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-LPIN1 Antibody (6D73) is a Rabbit antibody targeting LPIN1. Anti-LPIN1 Antibody (6D73) can be used in WB,IP.
Ig Type
IgG
克隆号
6D73
反应种属
Human
应用WBIP
推荐剂量
WB: 1:500-2000; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位soform 1: Mitochondrion outer membrane. Cytoplasm. Nucleus membrane. Note=Recruited at the mitochondrion outer membrane following phosphatidic acid formation mediated by PLD6. In neuronals cells, isoform 1 is exclusively cytoplasmic. In 3T3-L1 pre-adipocytes, it primarily located in the cytoplasm. Isoform 2: Nucleus. Cytoplasm. Endoplasmic reticulum membrane. Note=Nuclear localization requires both CNEP1R1 and CTDNEP1. In neuronals cells, localized in both the cytoplasm and the nucleus. In 3T3-L1 pre-adipocytes, it is predominantly nuclear.
组织特异性Specifically expressed in skeletal muscle. Also expressed prominently in adipose tissue, and testis. Lower expression also detected in kidney, lung, brain and liver. Isoform 1 is the predominant isoform in the liver. Isoform 2 is the major form in the brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels
抗原信息
免疫原
A synthesized peptide: human LPIN1
抗原种属
Human
基因名称
LPIN1
基因ID
蛋白名称
Phosphatidate phosphatase LPIN1
Uniprot ID
功能
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
化学信息
分子量Theoretical: 99 kDa. Actual: 130 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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