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别名 ZWS2, PXMP1, PXMP 1, PMP70, PMP 70, Peroxisomal membrane protein 1, ATP-binding cassette sub-family D member 3, ATP binding cassette sub family D(ALD) member 3, ATP binding cassette sub family D member 3, ABCD3_HUMAN, ABCD3 protein, ABCD 3, ABC43, ABC D3, ABC 43, 70 kDa peroxisomal membrane protein
Anti-ABCD3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ABCD3。Anti-ABCD3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-ABCD3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ABCD3。Anti-ABCD3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-ABCD3 Polyclonal Antibody is a Rabbit antibody targeting ABCD3. Anti-ABCD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| 别名 | ZWS2, PXMP1, PXMP 1, PMP70, PMP 70, Peroxisomal membrane protein 1, ATP-binding cassette sub-family D member 3, ATP binding cassette sub family D(ALD) member 3, ATP binding cassette sub family D member 3, ABCD3_HUMAN, ABCD3 protein, ABCD 3, ABC43, ABC D3, ABC 43, 70 kDa peroxisomal membrane protein |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 验证活性 | Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-PXMP1/ABCD3/PMP70 Polyclonal Antibody, Unconjugated (TMAB-02153) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Peroxisome membrane; Multi-pass membrane protein. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD1 localizes to peroxisomes. ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol. |
| 免疫原 | KLH conjugated synthetic peptide: human PXMP1/ABCD3 |
| 抗原种属 | Human |
| 基因名称 | ABCD3 |
| 基因ID | |
| 蛋白名称 | ATP-binding cassette sub-family D member 3 |
| Uniprot ID | |
| 功能 | Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. |
| 分子量 | Theoretical: 75 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |