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Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2

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产品编号 TMAB-10752

Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Gria2 (Ser880)。Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2

Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10752

Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-Gria2 (Ser880)。Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-Gria2 (Ser880). Anti-Phospho-Gria2 (Ser880) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Chicken,Cow,Horse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human Gria2 around the phosphorylation site of Ser880
抗原种属
Human
基因名称
GRIA2
基因ID
2891
蛋白名称
Glutamate receptor 2
Uniprot ID
P42262
功能
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
化学信息
分子量Theoretical: 96 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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