规格

价格

库存

数量

5 mg

¥ 133

现货

10 mg

¥ 176

现货

25 mg

¥ 265

现货

50 mg

¥ 373

现货

100 mg

¥ 549

现货

500 mg

¥ 822

现货

1 g

¥ 1,180

现货

1 mL x 10 mM (in DMSO)

¥ 197

现货

生物活性

产品描述	6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
体内活性	磷酸核糖焦磷酸酰胺转移酶是嘌呤合成的限速酶,可改变RNA和DNA的合成和功能。Mercaptopurine通过抑制磷酸核糖焦磷酸酰胺转移酶而抑制嘌呤核苷和代谢,能够干扰核苷酸的互变和糖蛋白的合成。
别名	Mercaptopurine, 6-巯基嘌呤,乐疾宁, 6-巯基嘌呤, 6-MP

化学信息

储存&溶解度

存储

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 41.67 mg/mL (273.82 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (6.57 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO