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BTLA Protein, Cynomolgus, Recombinant (His)

Synonyms: MGC129743, FLJ16065, CD272, BTLA1, BTLA
货号 TMPK-00530 一键复制产品信息
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B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.04 kDa and the accession number is A0A2K5W7M7.

BTLA Protein, Cynomolgus, Recombinant (His)

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货号 TMPK-00530

别名 MGC129743, FLJ16065, CD272, BTLA1, BTLA

B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.04 kDa and the accession number is A0A2K5W7M7.

BTLA Protein, Cynomolgus, Recombinant (His)
其他形式的 “BTLA Protein, Cynomolgus, Recombinant (His)”:
规格价格库存数量
5 μg
¥ 358
6-8日内发货
10 μg
¥ 573
6-8日内发货
20 μg
¥ 938
5日内发货
50 μg
¥ 1,830
5日内发货
100 μg
¥ 3,100
5日内发货
200 μg
¥ 5,620
5日内发货
500 μg
¥ 12,400
5日内发货
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产品介绍


生物活性
产品描述
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.04 kDa and the accession number is A0A2K5W7M7.
生物活性
Immobilized Cynomolgus BTLA, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-BTLA Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA.
研究背景
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.
种属
Cynomolgus
表达系统
HEK293 Cells
标签
C-His
蛋白编号A0A2K5W7M7
蛋白构建
Lys31-Pro152
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状
Lyophilized powder
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
MGC129743, FLJ16065, CD272, BTLA1, BTLA
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量15.04 kDa (predicted). Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

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