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Anti-Dystrobrevin alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dystrobrevin alpha。Anti-Dystrobrevin alpha Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
Anti-Dystrobrevin alpha Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dystrobrevin alpha。Anti-Dystrobrevin alpha Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Dystrobrevin alpha Polyclonal Antibody is a Rabbit antibody targeting Dystrobrevin alpha. Anti-Dystrobrevin alpha Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Dog,Horse) |
| 应用 | IHC-PIHC-FrICC/IFIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cell projection, growth cone. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. |
| 组织特异性 | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Dystrobrevin alpha belongs to the dystrobrevin subfamily of the dystrophin family. It is a component of the dystrophin associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha and beta dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin alpha may be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. Mutations in Dystrobrevin alpha are associated with left ventricular noncompaction with congenital heart defects. |
| 免疫原 | KLH conjugated synthetic peptide: mouse Dystrobrevin alpha |
| 抗原种属 | Mouse |
| 基因名称 | DTNA |
| 基因ID | |
| 蛋白名称 | Dystrobrevin alpha |
| Uniprot ID | |
| 功能 | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration . |
| 分子量 | Theoretical: 81 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |