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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DUOX1 Polyclonal Antibody

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货号 TMAB-05335

Anti-DUOX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUOX1。Anti-DUOX1 Polyclonal Antibody 可用于 WB。

Anti-DUOX1 Polyclonal Antibody

Anti-DUOX1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05335

Anti-DUOX1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUOX1。Anti-DUOX1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-DUOX1 Polyclonal Antibody is a Rabbit antibody targeting DUOX1. Anti-DUOX1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane of epithelial cells.
组织特异性Expressed in thyrocytes and tracheal surface epithelial cells (at protein level). Expressed in thyroid, trachea, bronchium, and to a lower extent, in placenta, testis, prostate, pancreas and heart.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DUOX1
抗原种属
Human
基因名称
DUOX1
基因ID
53905
蛋白名称
Dual oxidase 1
Uniprot ID
Q9NRD9
功能
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene).
化学信息
分子量Theoretical: 175 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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