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Anti-IL-11R alpha/IL-11RA Antibody (7B753)
还可以产品编号 TMAY-03080
Anti-IL-11R alpha/IL-11RA Antibody (7B753) 是一种 Rabbit 抗体，靶向 IL-11R alpha/IL-11RA。Anti-IL-11R alpha/IL-11RA Antibody (7B753) 可用于 ELISA。
Anti-IL-11R alpha/IL-11RA Antibody (7B753)
Anti-IL-11R alpha/IL-11RA Antibody (7B753)
还可以产品编号 TMAY-03080
Anti-IL-11R alpha/IL-11RA Antibody (7B753) 是一种 Rabbit 抗体，靶向 IL-11R alpha/IL-11RA。Anti-IL-11R alpha/IL-11RA Antibody (7B753) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-11R alpha/IL-11RA Antibody (7B753) is a Rabbit antibody targeting IL-11R alpha/IL-11RA. Anti-IL-11R alpha/IL-11RA Antibody (7B753) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7B753 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL11RA (rM IL11RA; TMPY-01250; NP_001156873.1; Met 1-Gln 367) . |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. This particular receptor is very similar to the ciliary neurotrophic factor since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified. IL11RA/IL-11RA is a receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11, and CT1 can utilize IL6ST for initiating signal transmission. Defects in IL11RA/IL-11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse IL11RA protein (TMPY-01250) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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