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Anti-IL-11R alpha/IL-11RA Antibody (7B753)

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Anti-IL-11R alpha/IL-11RA Antibody (7B753)
产品编号 TMAY-03080
别名 interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA

Anti-IL-11R alpha/IL-11RA Antibody (7B753) 是一种 Rabbit 抗体,靶向 IL-11R alpha/IL-11RA。Anti-IL-11R alpha/IL-11RA Antibody (7B753) 可用于 ELISA。

Anti-IL-11R alpha/IL-11RA Antibody (7B753)

Anti-IL-11R alpha/IL-11RA Antibody (7B753)

Rating icon 还可以
Anti-IL-11R alpha/IL-11RA Antibody (7B753)
产品编号 TMAY-03080 别名 interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA

Anti-IL-11R alpha/IL-11RA Antibody (7B753) 是一种 Rabbit 抗体,靶向 IL-11R alpha/IL-11RA。Anti-IL-11R alpha/IL-11RA Antibody (7B753) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-IL-11R alpha/IL-11RA Antibody (7B753) is a Rabbit antibody targeting IL-11R alpha/IL-11RA. Anti-IL-11R alpha/IL-11RA Antibody (7B753) can be used in ELISA.
别名interleukin 11 receptor subunit α, interleukin 11 receptor subunit alpha, IL11RA
Ig Type
Rabbit IgG
克隆号
7B753
交叉反应
Mouse
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL11RA (rM IL11RA; TMPY-01250; NP_001156873.1; Met 1-Gln 367) .
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma. This particular receptor is very similar to the ciliary neurotrophic factor since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified. IL11RA/IL-11RA is a receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11, and CT1 can utilize IL6ST for initiating signal transmission. Defects in IL11RA/IL-11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse IL11RA protein (TMPY-01250)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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