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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SCXA Polyclonal Antibody

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货号 TMAB-01670

别名 SCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis

Anti-SCXA Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SCXA。Anti-SCXA Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-SCXA Polyclonal Antibody

Anti-SCXA Polyclonal Antibody

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货号 TMAB-01670 别名 SCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis

Anti-SCXA Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SCXA。Anti-SCXA Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-SCXA Polyclonal Antibody is a Rabbit antibody targeting SCXA. Anti-SCXA Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名SCXB, SCX, scleraxis homolog A, Class A basic helix-loop-helix protein 48, Class A basic helix-loop-helix protein 41, bHLHa48, bHLHa41, Basic helix-loop-helix transcription factor scleraxis
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse)
验证活性
Tissue/cell: rat thyroid gland; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-SCXA Polyclonal Antibody, Unconjugated (TMAB-01670) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains 1 bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SCXA
抗原种属
Human
基因名称
SCX
基因ID
642658
蛋白名称
Basic helix-loop-helix transcription factor scleraxis
Uniprot ID
Q7RTU7
功能
Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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