Name: Amphotericin X1
Brand: TargetMol
SKU: T10311
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 169,800

2-4周

生物活性

产品描述	Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
靶点活性	A.fumigatus:2 μg/mL , Aspergillus niger 57A: 2 μg/mL , Cryptococcus neoformans 451: 1 μg/mL , C.parapsilosis 937A: 8 μg/mL , C. albicans 33/079:（MIC）1 μg/mL
体外活性	Amphotericin X1 (compound 4) shows antifungal activity combined with a pronounced reduction in hemolytic activity (EH50: 42 μg/mL) against mammalian erythrocytes in vitro.
别名	两性霉素 X1

化学信息

分子量	938.118
分子式	C₄₈H₇₅NO₁₇
CAS No.	136135-57-4
Smiles	[H][C@]12C[C@@H](O[C@]3([H])O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@@](C[C@H](O)[C@H]1C(O)=O)(OC)O2 \|t:17,19,21,23,25,27,29\|
密度	1.31 g/cm3 (Predicted)