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Anti-CD2 Antibody-FITC (8W59)
还可以产品编号 TMAY-01418F
Anti-CD2 Antibody-FITC (8W59) 是一种 FITC-conjugated Mouse 抗体，靶向 CD2。Anti-CD2 Antibody-FITC (8W59) 可用于 FCM。
Anti-CD2 Antibody-FITC (8W59)
Anti-CD2 Antibody-FITC (8W59)
还可以产品编号 TMAY-01418F
Anti-CD2 Antibody-FITC (8W59) 是一种 FITC-conjugated Mouse 抗体，靶向 CD2。Anti-CD2 Antibody-FITC (8W59) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD2 Antibody-FITC (8W59) is a FITC-conjugated Mouse antibody targeting CD2. Anti-CD2 Antibody-FITC (8W59) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8W59 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human CD2 expression on human whole blood lymphocytes. Human whole blood lymphocytes were stained with FITC-conjugated anti-Human CD2. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells, and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PerCP/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human CD2 protein (TMPY-01255) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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