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顶部生物活性储存和溶解信息计算器

Anti-APC Antibody (8V676)

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Anti-APC Antibody (8V676)
产品编号 TMAC-00237
别名 Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein

Anti-APC Antibody (8V676) 是一种 Rabbit 抗体，靶向 APC。Anti-APC Antibody (8V676) 可用于 WB,ICC,IP。

Anti-APC Antibody (8V676)

Anti-APC Antibody (8V676)

Rating icon 还可以
Anti-APC Antibody (8V676)
产品编号 TMAC-00237 别名 Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein

Anti-APC Antibody (8V676) 是一种 Rabbit 抗体，靶向 APC。Anti-APC Antibody (8V676) 可用于 WB,ICC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-APC Antibody (8V676) is a Rabbit antibody targeting APC. Anti-APC Antibody (8V676) can be used in WB,ICC,IP.
别名Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein
Ig Type
IgG
交叉反应
Human,Rat
验证活性
1. Western blot analysis of APC on mouse brain lysates using anti-APC antibody at 1/1,000 dilution.
2. ICC staining APC in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining APC in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
IP
推荐剂量
WB: 1:1000-5000; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner??s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2,843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. β-catenin and γ-catenin (also called plakoglobin), are involved in the regulation of cellular adhesion. APC and E-cadherin compete for binding to specific internal regions of both β- and γ-catenin. Interactions between cytoskeleton and the APC, E-cadherin, β/γ catenin complex are mediated by α-catenin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P25054
化学信息
分子量Theoretical: 160 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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