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Anti-KDM3A Antibody (5B591)

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Anti-KDM3A Antibody (5B591)
产品编号 TMAC-02301
别名 TSGA, Testis specific protein A, Lysine-specific demethylase 3A, Lysine (K) specific demethylase 3A, KIAA0742, KDM3A_HUMAN, Kdm 3a, Jumonji domain-containing protein 1A, Jumonji domain containing protein 1A, Jumonji domain containing 1A, Jumonji domain containing 1, Jumonji C domain containing histone demethylase 2A, JMJD1A, JMJD1, JmjC domain-containing histone demethylation protein 2A, JHMD2A, JHDM2A, DKFZp686P07111, DKFZp686A24246

Anti-KDM3A Antibody (5B591) 是一种 Mouse 抗体,靶向 KDM3A。Anti-KDM3A Antibody (5B591) 可用于 WB,ICC,FCM。

Anti-KDM3A Antibody (5B591)

Anti-KDM3A Antibody (5B591)

Rating icon 还可以
Anti-KDM3A Antibody (5B591)
产品编号 TMAC-02301 别名 TSGA, Testis specific protein A, Lysine-specific demethylase 3A, Lysine (K) specific demethylase 3A, KIAA0742, KDM3A_HUMAN, Kdm 3a, Jumonji domain-containing protein 1A, Jumonji domain containing protein 1A, Jumonji domain containing 1A, Jumonji domain containing 1, Jumonji C domain containing histone demethylase 2A, JMJD1A, JMJD1, JmjC domain-containing histone demethylation protein 2A, JHMD2A, JHDM2A, DKFZp686P07111, DKFZp686A24246

Anti-KDM3A Antibody (5B591) 是一种 Mouse 抗体,靶向 KDM3A。Anti-KDM3A Antibody (5B591) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,990
5日内发货
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产品介绍

生物活性
产品描述
Anti-KDM3A Antibody (5B591) is a Mouse antibody targeting KDM3A. Anti-KDM3A Antibody (5B591) can be used in WB,ICC,FCM.
别名TSGA, Testis specific protein A, Lysine-specific demethylase 3A, Lysine (K) specific demethylase 3A, KIAA0742, KDM3A_HUMAN, Kdm 3a, Jumonji domain-containing protein 1A, Jumonji domain containing protein 1A, Jumonji domain containing 1A, Jumonji domain containing 1, Jumonji C domain containing histone demethylase 2A, JMJD1A, JMJD1, JmjC domain-containing histone demethylation protein 2A, JHMD2A, JHDM2A, DKFZp686P07111, DKFZp686A24246
交叉反应
Human
验证活性
1. Western blot analysis of KDM3A on human KDM3A recombinant protein using anti-KDM3A antibody at 1/1,000 dilution.
2. Western blot analysis of KDM3A on HEK293 (1) and KDM3A-hIgGFc transfected HEK293 (2) cell lysate using anti-KDM3A antibody at 1/1,000 dilution.
3. ICC staining KDM3A (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with KDM3A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景JMJD1A (Jumonji domain containing 1A), also known as TSGA (testis-specific protein A), JMJD1, KDM3A, JHDM2A (JMJC domain-containing histone demethylation protein 2A) or JHMD2A, is a member of the JHDM2 histone demethylase family of proteins that is predominantly expressed in testis. Containing one JMJC domain and a C-terminal C2HC4 zinc finger, JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and a-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 147 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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