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CD82 Protein, Human, Recombinant (hFc)

CD82 Protein, Human, Recombinant (hFc)

产品编号 TMPJ-00157
别名: Tetraspanin-27, KAI1, ST6, TSPAN27, TSPAN274F9, CD82 molecule, Tspan-27, IA4, IA4C33 antigen, ST6tspan-27, Suppressor of tumorigenicity 6 protein, CD82 antigenC33, KAI1GR15, Inducible membrane protein R2, CD82

CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

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CD82 Protein, Human, Recombinant (hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 1,000 5日内发货
50 μg ¥ 3,040 5日内发货
500 μg ¥ 15,200 5日内发货
1 mg ¥ 22,900 5日内发货
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产品目录号及名称: CD82 Protein, Human, Recombinant (hFc) (TMPJ-00157)
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产品描述 CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
种属 Human
表达系统 HEK293 Cells
标签 N-hFc
蛋白编号 P27701
别名 Tetraspanin-27, KAI1, ST6, TSPAN27, TSPAN274F9, CD82 molecule, Tspan-27, IA4, IA4C33 antigen, ST6tspan-27, Suppressor of tumorigenicity 6 protein, CD82 antigenC33, KAI1GR15, Inducible membrane protein R2, CD82
氨基酸序列 Gly103-Gln225
蛋白构建 Gly103-Gln225
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 40-60 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

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Keywords

CD82 Protein, Human, Recombinant (hFc) ST 6 IA-4 Tetraspanin-27 CD-82 KAI1 ST6 TSPAN27 TSPAN274F9 CD82 molecule KAI-1 Tspan-27 TSPAN-27 IA4 CD 82 IA4C33 antigen ST6tspan-27 TSPAN 27 ST-6 Suppressor of tumorigenicity 6 protein KAI 1 CD82 antigenC33 IA 4 KAI1GR15 Inducible membrane protein R2 CD82 recombinant recombinant-proteins proteins protein

 

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