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Anti-CD73 Antibody-PE (9U110)
还可以产品编号 TMAY-01317P
Anti-CD73 Antibody-PE (9U110) 是一种 PE-conjugated Mouse 抗体，靶向 CD73。Anti-CD73 Antibody-PE (9U110) 可用于 FCM。
Anti-CD73 Antibody-PE (9U110)
Anti-CD73 Antibody-PE (9U110)
还可以产品编号 TMAY-01317P
Anti-CD73 Antibody-PE (9U110) 是一种 PE-conjugated Mouse 抗体，靶向 CD73。Anti-CD73 Antibody-PE (9U110) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-CD73 Antibody-PE (9U110) is a PE-conjugated Mouse antibody targeting CD73. Anti-CD73 Antibody-PE (9U110) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9U110 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human NT5E(CD73) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human NT5E(CD73). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD73 / NT5E (rh CD73 / NT5E; TMPY-01851; NP_002517.1; Met1-Lys547) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | 5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surface of human T and B lymphocytes. CD73 catalyzes the conversion of purine and pyrimidine ribo- and deoxyribonucleoside monophosphates to the corresponding nucleosides. CD73 serves as a costimulatory molecule in activating T cells. CD73 generated adenosine functions in cell signaling in many physiologic systems, including intestinal epithelium, ischemic myocardium, and cholinergic synapses. CD73 might mediate lymphocyte-stromal cell interactions or condition the local microenvironment to facilitate lymphocyte development and/or function. In CD73-depleted cells, surface levels of the leukocyte adhesion molecules ICAM-1, VCAM-1, and E-selectin increase. CD73 produces extracellular adenosine, which then acts on G protein-coupled purinergic receptors to induce cellular responses. CD73 has also been reported to regulate the expression of pro-inflammatory molecules in mouse endothelium. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/FITC |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human CD73 / NT5E Protein (TMPY-01851) |
| 抗原种属 | Human |
| 研究领域 | Phosphatases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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