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顶部生物活性储存和溶解信息计算器

Anti-CD73 Antibody-PE (9U110)

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产品编号 TMAY-01317P

别名 NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)

Anti-CD73 Antibody-PE (9U110) 是一种 PE-conjugated Mouse 抗体，靶向 CD73。Anti-CD73 Antibody-PE (9U110) 可用于 FCM。

Anti-CD73 Antibody-PE (9U110)

Anti-CD73 Antibody-PE (9U110)

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Rating icon 还可以
产品编号 TMAY-01317P 别名 NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)

Anti-CD73 Antibody-PE (9U110) 是一种 PE-conjugated Mouse 抗体，靶向 CD73。Anti-CD73 Antibody-PE (9U110) 可用于 FCM。

规格价格库存数量
25 T
¥ 895
5日内发货
100 T
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD73 Antibody-PE (9U110) is a PE-conjugated Mouse antibody targeting CD73. Anti-CD73 Antibody-PE (9U110) can be used in FCM.
别名NTE, NT5, NT, eNT, eN, E5NT, CD73, CALJA, 5'-nucleotidase, ecto (CD73)
Ig Type
Mouse IgG1
克隆号
9U110
交叉反应
Human
特异性
Human 5'-nucleotidase/CD73/NT5E
验证活性
Flow cytometric analysis of Human NT5E(CD73) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human NT5E(CD73). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD73 / NT5E (rh CD73 / NT5E; TMPY-01851; NP_002517.1; Met1-Lys547) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surface of human T and B lymphocytes. CD73 catalyzes the conversion of purine and pyrimidine ribo- and deoxyribonucleoside monophosphates to the corresponding nucleosides. CD73 serves as a costimulatory molecule in activating T cells. CD73 generated adenosine functions in cell signaling in many physiologic systems, including intestinal epithelium, ischemic myocardium, and cholinergic synapses. CD73 might mediate lymphocyte-stromal cell interactions or condition the local microenvironment to facilitate lymphocyte development and/or function. In CD73-depleted cells, surface levels of the leukocyte adhesion molecules ICAM-1, VCAM-1, and E-selectin increase. CD73 produces extracellular adenosine, which then acts on G protein-coupled purinergic receptors to induce cellular responses. CD73 has also been reported to regulate the expression of pro-inflammatory molecules in mouse endothelium.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/FITC
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human CD73 / NT5E Protein (TMPY-01851)
抗原种属
Human
研究领域
Phosphatases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

计算器

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关键词

NT-5NT 5CD-73CD 735'-nucleotidase, ecto

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