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顶部生物活性储存和溶解信息计算器

Anti-CD45 Antibody (8L304)

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产品编号 TMAH-01024

别名 T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220

Anti-CD45 Antibody (8L304) 是一种抗体，靶向 CD45。Anti-CD45 Antibody (8L304) 可用于 ELISA,FCM。

Anti-CD45 Antibody (8L304)

Anti-CD45 Antibody (8L304)

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Rating icon 还可以
产品编号 TMAH-01024 别名 T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220

Anti-CD45 Antibody (8L304) 是一种抗体，靶向 CD45。Anti-CD45 Antibody (8L304) 可用于 ELISA,FCM。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD45 Antibody (8L304) is an antibody targeting CD45. Anti-CD45 Antibody (8L304) can be used in ELISA,FCM.
别名T200, PTPRC, LY5, L-CA, LCA, GP180, EC 3.1.3.48, CD45R, CD45, B220
Ig Type
Mouse IgG2a
克隆号
8L304
交叉反应
Human
验证活性
Overlay Peak curve showing 293 cells surface stained with TMAH-01024 (red line) at 1:100. Then 10% normal goat serum was Incubated to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
应用ELISAFCM
推荐剂量
FCM:1:20-1:500.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein. Membrane raft.
组织特异性Isoform 1: Detected in thymocytes. Isoform 2: Detected in thymocytes. Isoform 3: Detected in thymocytes. Isoform 4: Not detected in thymocytes. Isoform 5: Detected in thymocytes. Isoform 6: Not detected in thymocytes. Isoform 7: Detected in thymocytes. Is
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human PTPRC Protein
抗原种属
Human
基因名称
PTPRC
基因ID
5788
Uniprot ID
P08575
研究领域
Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

T-200T 200LY-5LY 5GP-180GP 180CD-45CD 45B-220B 220

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4个月前
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