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K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)

K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)

产品编号 T36577
别名: K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)

Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B also has lysine residues at positions 108, 116, and 120 that are subject to acetylation.2

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T36577
K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt), CAS N/A
规格 价格/CNY 货期 数量
1 mg ¥ 4,526 待询
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产品目录号及名称: K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt) (T36577)
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参考文献
产品描述 Histone H2B (108-125) is a peptide fragment of histone H2B that corresponds to amino acid residues 109-126 of the human histone H2B sequence. It contains an N-terminal biotinylated lysine followed by a tryptophan linker. Histone H2B can be modified by addition of an O-linked N-acetylglucosamine (GlcNAc) moiety to the serine residue at position 112, which promotes monoubiquitination of the lysine at position 120.1 Both of these modifications are associated with active transcription. Histone H2B also has lysine residues at positions 108, 116, and 120 that are subject to acetylation.2
别名 K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt)
分子量 N/A

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度

H2O: 1 mg/mL

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TargetMol Library Books参考文献

1. Fujiki, R., Hashiba, W., Sekine, H., et al. GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature 480(7378), 557-560 (2011). 2. Portela, A., and Esteller, M. Epigenetic modifications and human disease. Nat. Biotechnol. 28(10), 1057-1068 (2010).

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请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。

Keywords

K-Biotin-W-Histone H2B (108-125) (trifluoroacetate salt) KBiotinWHistone H2B (108125) (trifluoroacetate salt) K-Biotin-W-Histone H-2B (108-125) (trifluoroacetate salt) K-Biotin-W-Histone H2B K Biotin W Histone H2B (108 125) (trifluoroacetate salt) Inhibitor inhibitor inhibit

 

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