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Anti-PD-L1 Polyclonal Antibody

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Anti-PD-L1 Polyclonal Antibody
产品编号 TMAB-01359

Anti-PD-L1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PD-L1。Anti-PD-L1 Polyclonal Antibody 可用于 WB。

Anti-PD-L1 Polyclonal Antibody

Anti-PD-L1 Polyclonal Antibody

Rating icon 还可以
Anti-PD-L1 Polyclonal Antibody
产品编号 TMAB-01359

Anti-PD-L1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PD-L1。Anti-PD-L1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PD-L1 Polyclonal Antibody is a Rabbit antibody targeting PD-L1. Anti-PD-L1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Pig,Cow,Horse,Sheep)
验证活性
Sample:
Du145 (Human) Cell Lysate at 30 μg
LOVO (Human) Cell Lysate at 30 μg
Heart (Mouse) Lysate at 40 μg
Muscle (Mouse) Lysate at 40 μg
Heart (Rat) Lysate at 40 μg
Primary: Anti-PD-L1 (TMAB-01359) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Endomembrane system; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD274
抗原种属
Human
基因ID
Uniprot ID
研究领域
Tumor antigens,Tumor-associated antigens,Non-lineage,Autoimmune,pd-l1
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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