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Anti-CDCP1 Antibody (2K468)

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Anti-CDCP1 Antibody (2K468)
产品编号 TMAY-03550
别名 TRASK, SIMA135, CUB domain containing protein 1, CD318

Anti-CDCP1 Antibody (2K468) 是一种 Rabbit 抗体,靶向 CDCP1。Anti-CDCP1 Antibody (2K468) 可用于 ELISA(Cap)。

Anti-CDCP1 Antibody (2K468)
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Anti-CDCP1 Antibody (2K468)

Rating icon 还可以
Anti-CDCP1 Antibody (2K468)
产品编号 TMAY-03550 别名 TRASK, SIMA135, CUB domain containing protein 1, CD318

Anti-CDCP1 Antibody (2K468) 是一种 Rabbit 抗体,靶向 CDCP1。Anti-CDCP1 Antibody (2K468) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,294
5日内发货
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产品介绍

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产品描述
Anti-CDCP1 Antibody (2K468) is a Rabbit antibody targeting CDCP1. Anti-CDCP1 Antibody (2K468) can be used in ELISA(Cap).
别名TRASK, SIMA135, CUB domain containing protein 1, CD318
Ig Type
Rabbit IgG
克隆号
2K468
交叉反应
Mouse
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CDCP1 (rM CDCP1; TMPY-02901; Q5U462; Met1-Leu666).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migration of ovarian cancer Caov3 and OVCA420 cells with concomitant up-regulation of CDCP1 mRNA and protein. Consistent with a role in cell migration CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGFR. It may be involved in cell adhesion and cell matrix association. It also may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. It has been taken as a novel marker for leukemia diagnosis and immature hematopoietic stem cell subsets.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse CDCP1 Protein (TMPY-02901)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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