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Anti-Contactin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Contactin 1。Anti-Contactin 1 Polyclonal Antibody 可用于 FCM。
Anti-Contactin 1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Contactin 1。Anti-Contactin 1 Polyclonal Antibody 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Contactin 1 Polyclonal Antibody is a Rabbit antibody targeting Contactin 1. Anti-Contactin 1 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) |
| 应用 | FCM |
| 推荐剂量 | FCM: 3μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. |
| 组织特异性 | Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| 免疫原 | KLH conjugated synthetic peptide: human Contactin 1 |
| 抗原种属 | Human |
| 基因名称 | CNTN1 |
| 基因ID | |
| 蛋白名称 | Contactin-1 |
| Uniprot ID | |
| 功能 | Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). |
| 分子量 | Theoretical: 111 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |