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Anti-Neuroligin-1 Antibody (9M817)
还可以产品编号 TMAY-01940
别名 Nlg1, NL1, neuroligin 1, mKIAA1070, BB179718, 6330415N05Rik
Anti-Neuroligin-1 Antibody (9M817) 是一种 Rabbit 抗体，靶向 Neuroligin-1。Anti-Neuroligin-1 Antibody (9M817) 可用于 IHC-P。
Anti-Neuroligin-1 Antibody (9M817)
Anti-Neuroligin-1 Antibody (9M817)
还可以产品编号 TMAY-01940 别名 Nlg1, NL1, neuroligin 1, mKIAA1070, BB179718, 6330415N05Rik
Anti-Neuroligin-1 Antibody (9M817) 是一种 Rabbit 抗体，靶向 Neuroligin-1。Anti-Neuroligin-1 Antibody (9M817) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Neuroligin-1 Antibody (9M817) is a Rabbit antibody targeting Neuroligin-1. Anti-Neuroligin-1 Antibody (9M817) can be used in IHC-P. |
| 别名 | Nlg1, NL1, neuroligin 1, mKIAA1070, BB179718, 6330415N05Rik |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9M817 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human NLGN1 in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Neuroligin 1 / NLGN1 (rh Neuroligin 1 / NLGN1; TMPY-01726; NP_055747.1; Met1-Ser677). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Neuroligin 1 (NLGN1) belongs to the type-B carboxylesterase/lipase family, is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. Neuroligins consists of five members (NLGN1, NLGN2, NLGN3, NLGN4, and NLGN4Y), which interact with beta-neurexins, and this interaction is involved in the formation of functional synapses. The extracellular domain of functional Neuroligin 1 associates as a dimer when analyzed by sedimentation equilibrium. Neuroligin 1 has a unique N-linked glycosylation pattern in the neuroligin family, and glycosylation and its processing modify neuroligin activity. Neuroligin 1 is a potent trigger for the de novo formation of synaptic connections, and it has recently been suggested that it is required for the maturation of functionally competent excitatory synapses. The persistent expression of Neuroligin 1 is required for the maintenance of NMDAR-mediated synaptic transmission, which enables the normal development of synaptic plasticity and long-term memory in the amygdala of adult animals. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Neuroligin 1 / NLGN1 protein (TMPY-01726) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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