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Anti-CD31/PECAM-1 Antibody (7H367) 是一种 Mouse 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (7H367) 可用于 IHC-P。
Anti-CD31/PECAM-1 Antibody (7H367) 是一种 Mouse 抗体,靶向 CD31/PECAM-1。Anti-CD31/PECAM-1 Antibody (7H367) 可用于 IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,679 | 5日内发货 |
产品描述 | Anti-CD31/PECAM-1 Antibody (7H367) is a Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (7H367) can be used in IHC-P. |
别名 | platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791 |
Ig Type | Mouse IgG1 |
克隆号 | 7H367 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human CD31 in human liver with mouse monoclonal antibody (1:500, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human CD31 in human placenta with mouse monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:250-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31/PECAM-1 (rh CD31/PECAM-1; EAW94208.1; Met1-Lys601). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: Human CD31/PECAM-1 Protein |
抗原种属 | Human |
研究领域 | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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