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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HIPK2 Polyclonal Antibody

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货号 TMAB-07046

Anti-HIPK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIPK2。Anti-HIPK2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-HIPK2 Polyclonal Antibody

Anti-HIPK2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07046

Anti-HIPK2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIPK2。Anti-HIPK2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HIPK2 Polyclonal Antibody is a Rabbit antibody targeting HIPK2. Anti-HIPK2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, PML body. Cytoplasm.
组织特异性Highly expressed in heart, muscle and kidney. Weakly expressed in a ubiquitous way. Down-regulated in several thyroid and breast tumors.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Protein kinase acting as a corepressor of several transcription factors, including SMAD1 and POU4F1/Brn3a and probably NK homeodomain transcription factors. Inhibits cell growth and promotes apoptosis. Involved in transcriptional activation of TP53 and TP73. Phosphorylation of TP53 may be mediated by a TP53-HIPK2-AXIN1 complex. In response to TGFB, cooperates with DAXX to activate JNK. Phosphorylates the antiapoptotic factor CTBP1 and promotes its proteasomal degradation. In the Wnt/beta-catenin signaling pathway acts as an intermediate kinase between TAK1 and NLK to promote the proteasomal degradation of MYB (By similarity). Phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HIPK2
抗原种属
Human
基因ID
28996
Uniprot ID
Q9H2X6
化学信息
分子量Theoretical: 131 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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