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Anti-JUN Antibody (7A403) 是一种 Rabbit 抗体,靶向 JUN。Anti-JUN Antibody (7A403) 可用于 WB,ICC,IHC,IP。
Anti-JUN Antibody (7A403) 是一种 Rabbit 抗体,靶向 JUN。Anti-JUN Antibody (7A403) 可用于 WB,ICC,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-JUN Antibody (7A403) is a Rabbit antibody targeting JUN. Anti-JUN Antibody (7A403) can be used in WB,ICC,IHC,IP. |
别名 | V-jun avian sarcoma virus 17 oncogene homolog, Transcription factor Jun, Transcription factor AP-1 subunit Jun, Proto-oncogene c-Jun, p39, JUN, Activator protein 1 (AP1) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-c-Jun antibody. Counter stained with hematoxylin. 2. ICC staining c-Jun in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining c-Jun in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining c-Jun in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is inactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA). |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 43 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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