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Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
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还可以产品编号 TMAB-10725
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GAB2 (Ser159)。Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 可用于 WB。
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2
一键复制产品信息 还可以产品编号 TMAB-10725
Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-GAB2 (Ser159)。Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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| 产品描述 | Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-GAB2 (Ser159). Anti-Phospho-GAB2 (Ser159) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Chicken,Pig,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human GAB2 around the phosphorylation site of Ser159 |
| 抗原种属 | Human |
| 基因名称 | GAB2 |
| 基因ID | |
| 蛋白名称 | GRB2-associated-binding protein 2 |
| Uniprot ID | |
| 功能 | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
| 分子量 | Theoretical: 74 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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