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顶部生物活性储存和溶解信息计算器

Anti-Peroxiredoxin 6 Antibody (6V183)

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产品编号 TMAC-03416
别名 PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA2, 1-Cys

Anti-Peroxiredoxin 6 Antibody (6V183) 是一种 Rabbit 抗体，靶向 Peroxiredoxin 6。Anti-Peroxiredoxin 6 Antibody (6V183) 可用于 ICC/IF,IP,WB。

Anti-Peroxiredoxin 6 Antibody (6V183)

Anti-Peroxiredoxin 6 Antibody (6V183)

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Rating icon 还可以
产品编号 TMAC-03416 别名 PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA2, 1-Cys

Anti-Peroxiredoxin 6 Antibody (6V183) 是一种 Rabbit 抗体，靶向 Peroxiredoxin 6。Anti-Peroxiredoxin 6 Antibody (6V183) 可用于 ICC/IF,IP,WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Peroxiredoxin 6 Antibody (6V183) is a Rabbit antibody targeting Peroxiredoxin 6. Anti-Peroxiredoxin 6 Antibody (6V183) can be used in ICC/IF,IP,WB.
别名PRX, peroxiredoxin 6, p29, NSGPx, HEL-S-128m, AOP2, aiPLA2, 1-Cys
Ig Type
IgG
克隆号
6V183
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of PRDX6 on Jurkat cells lysates using anti-PRDX6 antibody at 1/500 dilution. Positive control: Line 1: Hela, Line 2:HepG2.
verifiedActivity
应用ICC/IFIPWB
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:10-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis. The human PRX IV gene is abundantly expressed in many tissues. PRX IV exists as a precursor protein, which is only detected in testis, and a processed secreted form. PRX V also exists as two forms, designated long and short. Like PRX IV, the long form of PRX V is highly expressed in testis. The short form of PRX V is more widely expressed, with high expression in liver, kidney, heart and lung. PRX VI, a 1-Cys peroxiredoxin (also known as antioxidant protein 2 or AOP2), is highly expressed in most tissues, particularly in epithelial cells. Localized to the cell cytosol, PRX VI functions independently of other peroxiredoxins and antioxidant proteins, specializing in antioxidant defense, lung phospholipid metabolism and protection of keratinocytes from cell death induced by reactive oxygen species.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P30041
化学信息
分子量Theoretical: 25 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

AOP-2AOP 2

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