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CXCR3 Protein, Human, Recombinant (GST & His)

CXCR3 Protein, Human, Recombinant (GST & His)

产品编号 TMPH-01162
别名: IP-10 receptor, CXCR3, CXC-R3, GPR9, Interferon-inducible protein 10 receptor, G protein-coupled receptor 9, CKR-L2, CD183, C-X-C chemokine receptor type 3, CXCR-3

CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli.

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CXCR3 Protein, Human, Recombinant (GST & His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,800 20日内发货
100 μg ¥ 3,420 20日内发货
1 mg ¥ 14,600 20日内发货
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产品目录号及名称: CXCR3 Protein, Human, Recombinant (GST & His) (TMPH-01162)
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生物活性
技术参数
产品性质
产品描述 CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
种属 Human
表达系统 E. coli
标签 N-6xHis-GST
蛋白编号 P49682
别名 IP-10 receptor, CXCR3, CXC-R3, GPR9, Interferon-inducible protein 10 receptor, G protein-coupled receptor 9, CKR-L2, CD183, C-X-C chemokine receptor type 3, CXCR-3
氨基酸序列 EVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLN
蛋白构建 4-50 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 36.6 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response.; Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival and angiogenic activity of human microvascular endothelial cells (HMVEC) through a cAMP-mediated signaling pathway. Does not promote cell chemotaxis respons. Interaction with CXCL4 or CXCL10 leads to activation of the p38MAPK pathway and contributes to inhibition of angiogenesis. Overexpression in renal cancer cells down-regulates expression of the anti-apoptotic protein HMOX1 and promotes apoptosis.; Mediates the activity of CXCL11.

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Keywords

CXCR3 Protein, Human, Recombinant (GST & His) IP-10 receptor CXCR3 CXC-R3 GPR9 Interferon-inducible protein 10 receptor G protein-coupled receptor 9 CKR-L2 CD183 C-X-C chemokine receptor type 3 CXCR-3 recombinant recombinant-proteins proteins protein

 

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