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别名 Sestrin1, SEST1, SEST 1, sesn1, PA26
Anti-Sestrin 1 Antibody (3U236) 是一种 Rabbit 抗体,靶向 Sestrin 1。Anti-Sestrin 1 Antibody (3U236) 可用于 FCM, WB。
Anti-Sestrin 1 Antibody (3U236) 是一种 Rabbit 抗体,靶向 Sestrin 1。Anti-Sestrin 1 Antibody (3U236) 可用于 FCM, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,950 | 5日内发货 | |
| 100 μL | ¥ 3,575 | 5日内发货 |
| 产品描述 | Anti-Sestrin 1 Antibody (3U236) is a Rabbit antibody targeting Sestrin 1. Anti-Sestrin 1 Antibody (3U236) can be used in FCM, WB. |
| 别名 | Sestrin1, SEST1, SEST 1, sesn1, PA26 |
| Ig Type | IgG |
| 克隆号 | 3U236 |
| 反应种属 | Human,Mouse,Rat |
| 特异性 | Sestrin 1 |
| 验证活性 | Western blot analysis of SESN1 expression in K562 cell lysate. |
| 应用 | FCMWB |
| 推荐剂量 | FCM: 1:20-1:100; WB: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Supplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. |
| 偶联 | Unconjugated |
| 免疫原 | A synthesized peptide: human Sestrin 1 |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |