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顶部生物活性储存和溶解信息计算器

Anti-BMP-4 Antibody (8A124)

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产品编号 TMAY-01027

别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (8A124) 是一种 Mouse 抗体，靶向 BMP-4。Anti-BMP-4 Antibody (8A124) 可用于 ELISA。

Anti-BMP-4 Antibody (8A124)

Anti-BMP-4 Antibody (8A124)

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Rating icon 还可以
产品编号 TMAY-01027 别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (8A124) 是一种 Mouse 抗体，靶向 BMP-4。Anti-BMP-4 Antibody (8A124) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-BMP-4 Antibody (8A124) is a Mouse antibody targeting BMP-4. Anti-BMP-4 Antibody (8A124) can be used in ELISA.
别名ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Ig Type
Mouse IgG2a
克隆号
8A124
交叉反应
Human
特异性
Human BMP4
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP4 (rh BMP4; TMPY-06842; P12644; Ser293-Arg408). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor (TGF-β) family of regulatory proteins, plays a crucial role in human malignancies. BMP4 treatment promoted HCC cells proliferation and induced autophagy. Mechanistic study revealed that the induction of autophagy by BMP4 was mediated through activating the JNK1/Bcl2 pathway. And the JNK1 inhibitor and knockdown of JNK1 could attenuate autophagy induced by BMP4 and eliminated BMP4-promoted HCC cells growth. BMP4 promoted HCC proliferation by autophagy activation through JNK1/Bcl-2 signaling.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human BMP4 Protein (TMPY-06842)
抗原种属
Human
研究领域
Early Mesodermal Lineage Markers, Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

OFC-11OFC 11MCOPS-6MCOPS 6

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