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Anti-TAB1 Antibody (3P371)

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货号 TMAB-13350

Anti-TAB1 Antibody (3P371) 是一种 Mouse 抗体，靶向 TAB1。Anti-TAB1 Antibody (3P371) 可用于 WB。

Anti-TAB1 Antibody (3P371)

Anti-TAB1 Antibody (3P371)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13350

Anti-TAB1 Antibody (3P371) 是一种 Mouse 抗体，靶向 TAB1。Anti-TAB1 Antibody (3P371) 可用于 WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-TAB1 Antibody (3P371) is a Mouse antibody targeting TAB1. Anti-TAB1 Antibody (3P371) can be used in WB.
Ig Type
IgG1, Kappa
克隆号
3P371
反应种属
Human,Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Mouse
组织特异性Ubiquitous.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
抗原信息
基因名称
TAB1
基因ID
10454
蛋白名称
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
功能
May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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