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IL-1F8 Protein, Human, Recombinant

产品编号 TMPY-02458

别名: FILI-(ETA), FIL1-(ETA), IL-1H2, IL1F8, IL1H2, FIL1, IL-1F8, interleukin 36, β, FIL1H, IL36B, interleukin 36, beta, IL1-ETA

IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NZH7-2.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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IL-1F8 Protein, Human, Recombinant

规格	价格/CNY		货期	数量
50 μg	￥ 2,940		5日内发货

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参考文献

生物活性	Testing in progress
产品描述	IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NZH7-2.

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	Q9NZH7-2
别名	FILI-(ETA), FIL1-(ETA), IL-1H2, IL1F8, IL1H2, FIL1, IL-1F8, interleukin 36, β, FIL1H, IL36B, interleukin 36, beta, IL1-ETA
蛋白构建	mature form of Human IL36B isofrom 2 (Q9NZH7-2) (Met 1-Glu 157)
蛋白纯度	> 97 % as determined by SDS-PAGE
分子量	17.7 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB.

参考文献

1. Magne D,et al. (2006) The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. Arthritis Research & Therapy. 8: R80. 2. Smith DE,et al. (2000) The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes. The Journal of Biological Chemistry. 275: 1169-75.

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Keywords

IL-1F8 Protein, Human, Recombinant FILI-(ETA) FIL1-(ETA) IL-1H2 IL1F8 IL1H2 FIL1 FIL-1 IL-1F8 interleukin 36, β FIL 1 FIL1H IL36B interleukin 36, beta IL1-ETA recombinant recombinant-proteins proteins protein

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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