Name: IL-1F8 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-02458
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 538

6-8日内发货

10 μg

¥ 858

6-8日内发货

20 μg

¥ 1,460

5日内发货

50 μg

¥ 3,380

5日内发货

生物活性

产品描述	IL-1F8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NZH7-2.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB.
种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	Q9NZH7-2
蛋白构建	A DNA sequence encoding the mature form of human IL36B isofrom 2 (Q9NZH7-2) (Met 1-Glu 157) was expressed. Predicted N terminal: Met
蛋白纯度	> 97 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	interleukin 36, β, interleukin 36, beta, IL36B, IL-1H2, IL1H2, IL-1F8, IL1F8, IL1-ETA, FILI-(ETA), FIL1H, FIL1-(ETA), FIL1
内毒素	Please contact us for more information.

化学信息

分子量	17.7 kDa (predicted); 18 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

IL-1F8 Protein, Human, Recombinant

IL-1F8 Protein, Human, Recombinant

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