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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-C5a anaphylatoxin Polyclonal Antibody

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货号 TMAB-03451

Anti-C5a anaphylatoxin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C5a anaphylatoxin。Anti-C5a anaphylatoxin Polyclonal Antibody 可用于 WB,FCM。

Anti-C5a anaphylatoxin Polyclonal Antibody

Anti-C5a anaphylatoxin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03451

Anti-C5a anaphylatoxin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 C5a anaphylatoxin。Anti-C5a anaphylatoxin Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-C5a anaphylatoxin Polyclonal Antibody is a Rabbit antibody targeting C5a anaphylatoxin. Anti-C5a anaphylatoxin Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Activation of the complement system plays a key role in normal inflammatory response to injury but may cause substantial injury when activated inappropriately. The complement system is activated either through the classical (antibody induced) or the alternative (microbial surface, polysacharride induced) pathway, both leading to the formation of the C5b9 complex. Fluid phase binding of the multifunctional glycoprotein S protein (vitronectin) to C5b9 leads to the formation of a cytolytically inactive complex, SC5b9, which is unable to attach to cells.
抗原信息
免疫原
Purified Human SC5b-9 Complex
抗原种属
Human
基因名称
C5
基因ID
727
蛋白名称
Complement C5
Uniprot ID
P01031
功能
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).
化学信息
分子量Theoretical: 8/109 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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