生物活性

产品描述	Cadherin 17/CDH17 Protein, Human, Recombinant (LlaFc) is expressed in HEK293 Cells. The accession number is Q12864-1.
生物活性	Immobilized Human CDH17, Llama IgG2b Fc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-CDH17 Antibody, hFc Avi Tag with the EC50 of 11.2 ng/ml determined by ELISA (QC Test).
研究背景	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
种属	Human
表达系统	HEK293 Cells
标签	C-Llama IgG2b Fc
蛋白编号	Q12864-1
蛋白构建	Gln23-Met787
蛋白纯度	> 90% as determined by Bis-Tris PAGE
缓冲液	Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
内毒素	< 0.1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	112.28 kDa (Predicted); 120-140 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

Cadherin 17/CDH17 Protein, Human, Recombinant (LlaFc)

Cadherin 17/CDH17 Protein, Human, Recombinant (LlaFc)

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