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Anti-LAMP2 Antibody (1I210)
还可以产品编号 TMAY-02603
Anti-LAMP2 Antibody (1I210) 是一种 Mouse 抗体，靶向 LAMP2。Anti-LAMP2 Antibody (1I210) 可用于 FCM。
Anti-LAMP2 Antibody (1I210)
Anti-LAMP2 Antibody (1I210)
还可以产品编号 TMAY-02603
Anti-LAMP2 Antibody (1I210) 是一种 Mouse 抗体，靶向 LAMP2。Anti-LAMP2 Antibody (1I210) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LAMP2 Antibody (1I210) is a Mouse antibody targeting LAMP2. Anti-LAMP2 Antibody (1I210) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1I210 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human LAMP2(CD107b) expression on Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human LAMP2(CD107b), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LAMP2/CD107b (rh LAMP2/CD107b; TMPY-04115; NP_054701.1; Met1-Ile375). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. LAMP2, also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. In humans, LAMP2, the causative gene of Danon disease, located on chromosome Xq24, encodes the lysosome-associated membrane protein-2 (LAMP-2). LAMP-2 deficiency, or Danon disease, is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. LAMP2 cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, which clinically resembles sarcomeric hypertrophic cardiomyopathy. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | FITC |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human LAMP2/CD107b Protein (TMPY-04115) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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