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Anti-PD-L1 Antibody (1N521)

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产品编号 TMAY-03025

Anti-PD-L1 Antibody (1N521) 是一种 Rabbit 抗体,靶向 PD-L1。Anti-PD-L1 Antibody (1N521) 可用于 ELISA。

Anti-PD-L1 Antibody (1N521)

Anti-PD-L1 Antibody (1N521)

Rating icon 还可以
产品编号 TMAY-03025

Anti-PD-L1 Antibody (1N521) 是一种 Rabbit 抗体,靶向 PD-L1。Anti-PD-L1 Antibody (1N521) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 795
5日内发货
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-PD-L1 Antibody (1N521) is a Rabbit antibody targeting PD-L1. Anti-PD-L1 Antibody (1N521) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
1N521
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PD-L1/B7-H1/CD274 (rM PD-L1/B7-H1/CD274; TMPY-01155; NP_068693.1; Met1-Thr238).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules and this protein contains one V-like and one C-like Ig domain within the extracellular domain, and together with PD-L2, are two ligands for PD1 which belongs to the CD28/CTLA4 family expressed on activated lymphoid cells. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Blockade: Blocking AntibodiImmune Checkpoint Blockade: PD-L1 / B7-H1 / CImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyPD-L1 / B7-H1 / CD274 Immune Checkpoint ProteTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse PD-L1/B7-H1/CD274 Protein (TMPY-01155)
抗原种属
Mouse
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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