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Anti-CD20 Antibody-PerCP (8W940)
还可以产品编号 TMAY-01445C
Anti-CD20 Antibody-PerCP (8W940) 是一种 PerCP-conjugated Rabbit 抗体，靶向 CD20。Anti-CD20 Antibody-PerCP (8W940) 可用于 FCM。
Anti-CD20 Antibody-PerCP (8W940)
Anti-CD20 Antibody-PerCP (8W940)
还可以产品编号 TMAY-01445C
Anti-CD20 Antibody-PerCP (8W940) 是一种 PerCP-conjugated Rabbit 抗体，靶向 CD20。Anti-CD20 Antibody-PerCP (8W940) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD20 Antibody-PerCP (8W940) is a PerCP-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PerCP (8W940) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8W940 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-CD20 reactivity on peripheral blood lymphocytes analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, Human CD20 Transfected CHO Cells and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed in all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections, and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells are usually in the normal range but can be very low.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | PerCP |
| 其他可选修饰符 | Unconjugated/APC/FITC/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | Human CD20 Transfected CHO Cells |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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